Limitations of MsQPCR

IMPACT OF RATIO-BASED SCORING:

The ERMI and ARMI scores are calculated based on the presence of specific molds categorized into two groups: Group 1 consists of molds associated with water-damaged homes, while Group 2 includes molds typically found in all homes. The score is derived from a comparison (or ratio) of these two groups, which can sometimes provide a misleading picture of a home’s total mold burden. Here’s how:

  • Higher Score, Not Necessarily Higher Mold Burden: A home could have a relatively higher score due to a higher presence of Group 1 molds compared to Group 2 molds, even if the total mold burden (the sum of all molds present) is not exceptionally high. This is because the score emphasizes the ratio rather than the absolute quantity of mold.
  • Lower Score with Higher Total Mold Burden: Conversely, a home might have a lower score if it has a large amount of Group 2 molds, even if the total mold burden is high. The presence of common molds can dilute the impact of water-damage-related molds in the scoring system, leading to a lower score despite a potentially unhealthy overall mold level.

This scoring mechanism can sometimes obscure the actual health risks associated with the total mold burden in a home, especially for individuals sensitive to a broader range of molds or those with conditions like CIRS.

INFLUENCE OF LOCAL ECOLOGIES ON MOLD SPECIES:

Local ecological conditions significantly influence which mold species are prevalent in a region, and thus, which molds might be found in homes within those areas. Factors such as climate (humidity, temperature), vegetation, and even the types of building materials used can affect the local mold flora. Here are a few ways how:

  • Climate: Humid climates might foster a different set of mold species compared to arid regions. Homes in areas with high humidity might be more prone to mold species that thrive in moist conditions, affecting the types of molds contributing to the ERMI score.
  • Vegetation and Surrounding Environment: The types of plants and trees surrounding a home can influence the types of mold spores found in the air and, subsequently, in the home. Different regions have distinct vegetation, leading to regional differences in mold species.
  • Building Practices and Materials: Regional differences in building materials and construction practices can also influence which molds are more likely to grow in homes. For example, materials that retain moisture could support different molds compared to more breathable materials.

Due to these factors, MSqPCR interpretation might vary by region. MSqPCR results could indicate a problem in one geographic area but be considered typical in another, based on the local ecology and common mold types.