There are three main types of DNA-based mold tests used in residential dust testing. While they share the same sampling method (MSqPCR), their purpose and scoring systems differ.

ERMI (Environmental Relative Moldiness Index)

Developed by the U.S. EPA, ERMI measures 36 mold species—26 associated with water damage (Group 1) and 10 found in typical homes (Group 2). The score is calculated by subtracting the total of Group 2 molds from the total of Group 1 molds.

• Pros: Broad mold panel, good for general home health screening
• Cons: Regional variability may affect accuracy; scoring can be confusing

HERTSMI-2

This simplified test focuses on just five mold species known to be significant for those with Chronic Inflammatory Response Syndrome (CIRS). It uses a point-based scoring system to determine whether a home is safe for reentry based on mold sensitivity.

• Pros: Targeted for health-sensitive individuals, easy-to-understand scoring
• Cons: Only detects five species; not useful for broader mold evaluation

Fungi 10

Developed with medical and environmental professionals, this test identifies 10 of the most impactful species for health and home exposure. It balances depth and simplicity, offering a clear look at concerning molds without the scoring complexities of ERMI.

• Pros: Focused, balanced panel; easier to interpret than ERMI
• Cons: Less standardized, fewer labs offer this format

Each test has value depending on the client’s needs. For general mold history, ERMI works well. For health-driven cases, HERTSMI-2 or Fungi 10 may be more appropriate.